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BI-D1870

SKU: orb1224926

Description

BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.

Images & Validation

Key Properties

CAS Number501437-28-1
MW391.42
Purity>98% (HPLC)
FormulaC19H23F2N5O2
SMILESO=C1N(C)C2=CN=C(NC3=CC(F)=C(O)C(F)=C3)N=C2N(CCC(C)C)C1C
TargetS6 Kinase
SolubilityDMSO:78 mg/mL (199.27 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BID1870 | BI D1870 | BI-D1870.

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BI-D1870 (orb1224926)

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200 mg
500 mg
5 mg
$ 210.00
10 mg
$ 310.00
25 mg
$ 480.00
50 mg
$ 670.00
100 mg
$ 920.00