BI-69A11

SKU: orb1305370

Description

BI-69A11 is a dual inhibitor of the AKT and NF-κB signaling pathways. This small molecule compound has been shown in research to sensitize colon cancer cells to growth inhibition by mda-7/IL-24 in vitro, making it a tool for studying oncogenic pathways and therapeutic resistance.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1233322-09-2
• MW: 425.87
• Purity: 96.97%
• Formula: C₂₅H₁₆ClN₃O₂
• SMILES: Clc1ccc2[nH]c(=O)c(C(=O)\C=C\c3nc4ccccc4[nH]3)c(-c3ccccc3)c2c1
• Target: NF-κB,Akt
• Solubility: DMSO:55 mg/mL (129.15 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NF-κB, NFκB, NFkB, NF-kB, (E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one, Akt, BI69A11, BI-69A11, BI-69A-11, BI 69A11

Compound Identifiers

PubChem CID

5343381