BI-6015

SKU: orb1940432

Description

BI 6015 is an antagonist of HNF4α. HNF4α is a nuclear receptor that regulates gene expression in the intestine cells, liver cells, and pancreas-β cells.

Key Properties

• CAS Number: 93987-29-2
• MW: 331.35
• Purity: >98% (HPLC)
• Formula: C₁₅H₁₃N₃O₄S
• SMILES: Cc1nc2ccccc2n1S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
• Solubility: In Vitro: DMSO : 50 mg/mL (150.90 mM)

Bioactivity

• In Vitro:
  Cell Viability Assay Cell line: Hep3B-Luc cells and primary hepatocytes. Concentration: 1.25, 2.5, 5, 10, 20 μM Incubation time: 24, 48, 72 hours. Result: Was markedly toxic to Hep3B cells but spared primary hepatocytes.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BI 6015 | BI6015