BI-2493

• Catalog Number: orb1737459
• Category: Small Molecules
• Description: BI-2493
• CAS Number: 2937344-16-4
• Purity: 0.98
• MW: 461.2
• SMILES: C[C@H]1CNCCN1C2=NC=CC(=N2)C3=NOC4=C3CCC[C@@]45CCCC6=C5C(=C(S6)N)C#N??
• Formula: C₂₄H₂₇N₇OS
• Biological Activity: BI-2493 is a potent and highly selective non-covalent pan-KRAS inhibitor, a structural analogue of BI-2865, that inhibits no more than 30% of the commonly analyzed safety targets. BI-2493 inhibited ERK phosphorylation and suppressed the expression of DUSP6 messenger RNA in tumor models.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.