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BGP-15

SKU: orb1224295

Description

A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro; has no effect on HSP90 levels, markedly increases the phosphorylation of HSF1 and expression of HSF1 and HSP72 in adipocytes and muscle cells; protects against obesity-induced insulin resistance and orally active; alleviates ventilation-induced diaphragm dysfunction associated with HSP72 induction and PARP-1 inhibition.Diabetes Phase 2 Clinical.

Images & Validation

Key Properties

CAS Number66611-37-8
MW351.272
Purity>98% (HPLC)
FormulaC14H24Cl2N4O2
SMILESC1CCN(CC1)CC(CON=C(C2=CN=CC=C2)N)O.Cl.Cl
TargetPARP
SolubilityDMSO: 11.33 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

BGP 15 | BGP15

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    C14H24Cl2N4O2

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Protocol Information

BGP-15 (orb1224295)

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Available Sizes

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200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 110.00
10 mg
$ 160.00
25 mg
$ 290.00
50 mg
$ 500.00
100 mg
$ 640.00