BGP-15

SKU: orb1224295

Description

A PARP inhibitor and an inducer of HSF-1/HSP72 (cotreatment with heat) in vtiro; has no effect on HSP90 levels, markedly increases the phosphorylation of HSF1 and expression of HSF1 and HSP72 in adipocytes and muscle cells; protects against obesity-induced insulin resistance and orally active; alleviates ventilation-induced diaphragm dysfunction associated with HSP72 induction and PARP-1 inhibition.Diabetes Phase 2 Clinical.

Key Properties

• CAS Number: 66611-37-8
• MW: 351.272
• Purity: >98% (HPLC)
• Formula: C₁₄H₂₄Cl₂N₄O₂
• SMILES: C1CCN(CC1)CC(CON=C(C2=CN=CC=C2)N)O.Cl.Cl
• Target: PARP
• Solubility: DMSO: 11.33 mg/mL

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BGP 15 | BGP15

Quick Database Links

Gene Symbol

PARP