Bfl-1-IN-6

SKU: orb2945937

Description

Bfl-1-IN-6 (Compound 20) is a potent, orally bioavailable BFL1 inhibitor with a 19 nM IC50. It stabilizes BFL1 protein, induces caspase-3 cleavage, and exhibits in vivo antitumor efficacy in mouse models, supporting its use in cancer research targeting apoptosis pathways.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 3106363-91-8
• MW: 402.89
• Formula: C₂₂H₂₄ClFN₂O₂
• SMILES: C[C@@H](C1=CC=C(C=C1)Cl)N(C2=CC(=C(C=C2)O[C@@H]3CC[C@H](C3)N)F)C(=O)C=C
• Target: Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676981