BFH772

• Catalog Number: orb1304013
• Category: Small Molecules
• Description: BFH772
• CAS Number: 890128-81-1
• Purity: 99.36%
• MW: 439.39
• SMILES: C(NC1=CC(C(F)(F)F)=CC=C1)(=O)C=2C3=C(C=C(OC=4C=C(CO)N=CN4)C=C3)C=CC2
• Formula: C₂₃H₁₆F₃N₃O₃
• Biological Activity: BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.