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BFB78

SKU: orb3211400

Description

BFB78 is an inhibitor of the nsP2 protease that can cross the blood-brain barrier. It effectively and broadly inhibits purified nsP2 proteases from various alphaviruses, with IC50 values ranging from 21.6 nM (MAYV; Mayaro virus) to 130.7 nM (CHIKV; chikungunya virus). BFB78 blocks viral replication in cell culture systems and reduces viral titers in mouse brains. It is applicable for research related to Venezuelan equine encephalitis virus (VEEV) infection.

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Key Properties

TargetVirus Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information