BET/Aurora kinase-IN-1

SKU: orb2945021

Description

BET/Aurora kinase-IN-1 (Compound 38) is a dual BET and Aurora kinase inhibitor. It shows potent antiproliferative effects in vitro against multiple cancer cell lines and demonstrates significant in vivo efficacy, achieving tumor growth inhibition in xenograft models of renal and colon cancers.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2674064-32-3
• MW: 463.55
• Formula: C₂₅H₃₀FN₇O
• SMILES: CC1=C(C(=NN1C)C2CC2)C3=NC(NC=4C=C5C(=CC4)N(C)C(=O)[C@@H](C)N5C(C)C)=NC=C3F
• Target: Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166661357