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BET/Aurora kinase-IN-1

SKU: orb2945021

Description

BET/Aurora kinase-IN-1 (Compound 38) is a dual BET and Aurora kinase inhibitor. It shows potent antiproliferative effects in vitro against multiple cancer cell lines and demonstrates significant in vivo efficacy, achieving tumor growth inhibition in xenograft models of renal and colon cancers.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Images & Validation

Key Properties

CAS Number2674064-32-3
MW463.55
FormulaC25H30FN7O
SMILESCC1=C(C(=NN1C)C2CC2)C3=NC(NC=4C=C5C(=CC4)N(C)C(=O)[C@@H](C)N5C(C)C)=NC=C3F
TargetAurora Kinase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

BET/Aurora kinase-IN-1 (orb2945021)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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