Beta-Tocopherol

SKU: orb1297443

Description

This small molecule modulates phorbol 12-myristate 13-acetate (PMA)-induced adhesion in human erythroleukemia (HEL) cells. It is a research tool for studying cell adhesion mechanisms, signal transduction, and differentiation in hematological cancer models during in vitro experiments.

Research Area

Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 148-03-8
• MW: 416.68
• Purity: 99.92% (May vary between batches)
• Formula: C₂₈H₄₈O₂
• SMILES: CC1=C2C(CC[C@](CCC[C@@H](CCC[C@@H](CCCC(C)C)C)C)(C)O2)=C(C)C(O)=C1
• Target: Tyrosinase,MAPK,ERK
• Solubility: DMSO:75 mg/mL (179.99 mM)

Bioactivity

• In Vitro:
  METHODS: HEL cells were incubated with Beta-Tocopherol (50 μM) for 24 hours, then PMA (25 nM) was added and incubated for 30 minutes. RESULTS Beta-Tocopherol blocked 11% of the PMA-induced adhesion.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Tyrosinase, β-Tocopherol, vitamin E, b-Tocopherol, BetaTocopherol, Beta-Tocopherol, antioxidant, Beta Tocopherol, Inhibitor, MAPK, ERK, inhibit

Compound Identifiers

PubChem CID

6857447