beta-Escin

SKU: orb1298587

Description

Beta-Escin, a triterpenoid saponin mixture derived from horse chestnut seeds, exhibits vasoprotective, anti-inflammatory, anti-edematous, and anti-nociceptive properties. It is widely used in pharmacological research to study vascular permeability and inflammation models in both in vitro and in vivo experimental settings.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 11072-93-8
• MW: 1131.3
• Purity: 98.66% (May vary between batches)
• Formula: C₅₅H₈₆O₂₄
• SMILES: C\C=C(/C)C(=O)OC1[C@H](OC(C)=O)C2(CO)[C@H](O)C[C@]3(C)C(=CCC4C5(C)CCC(O[C@@H]6O[C@@H]([C@@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(O)=O)[C@](C)(CO)C5CCC34C)C2CC1(C)C
• Target: Immunology/Inflammation related
• Solubility: DMSO:33.33 mg/mL (29.46 mM)

Bioactivity

• In Vitro:
  Escin not only potentiated the proliferation-inhibiting and apoptosis-inducing effect of gemcitabine in both BxPC-3 and PANC-1 cell lines in vitro.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

fibroblast growth factor, Inhibitor, migration, inhibit, Inflammationrelated, Inflammation related, Immunology related, Immunology/Inflammation related, Immunologyrelated, anti-angiogenic, CAM angiogenesis, Aesculus hippocastanum L. seeds, AESCINE, beta Escin, B-escin, betaEscin, beta-Escin, tube formation, β-Escin, proliferation

Compound Identifiers

PubChem CID

16211024