Beta-Amyloid (1-42), FITC-labeled

SKU: orb3073173

Description

Peptide to Beta-Amyloid (1-42), FITC-labeled

Research Area

Neuroscience

Images & Validation

• Application Notes:
  Aβ 1-42, 42-residue fragment of amyloid precursor protein, has been found to be a major constituent of the senile plaques formed in the brains of patients with Alzheimer's disease and late Down's syndrome. Aβ 1-42 readily forms neurotoxic oligomers at physiological pH. The sequence corresponds to the human, bovine, canine, feline, ovine, guinea pig, and rabbit Aβ42 peptide. The peptide has been used to detect amyloid β-protein multimers in the cerebrospinal fluid of Alzheimer's disease patients through fluorescence correlation spectroscopy.

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Key Properties

• Source: Synthetic
• MW: 5016.57
• Purity: > 95%
• Formula: C₂₃₀H₃₃₃N₅₇O₆₆S₂
• Protein Sequence: FITC-Acp-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH

Storage & Handling

• Storage: Shipped at 4°C. Store at -20°C for one year.
• Form/Appearance: Liquid
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Aβ42