Berotralstat HCl

SKU: orb1739319

Description

Berotralstat HCl is a selective plasma kallikrein inhibitor that prevents bradykinin generation, the key mediator of swelling in hereditary angioedema (HAE). It is used in biochemical research to study kallikrein-kinin system pharmacology and has been evaluated in both in vitro enzymatic assays and in vivo preclinical models of HAE.

Research Area

Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 1809010-52-3
• MW: 635.4886
• Formula: C₃₀H₂₈Cl₂F₄N₆O
• SMILES: Cl.Cl.NCc1cccc(c1)-n1nc(cc1C(=O)Nc1cc(ccc1F)[C@H](NCC1CC1)c1cccc(c1)C#N)C(F)(F)F
• Target: Serine Protease,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139030242