(E/Z)-NiCur

SKU: orb1298344

Description

This compound is a potent p53 inhibitor with an IC50 of 0.35 µM. It is used in biochemical research to study p53-dependent pathways, facilitating in vitro investigations into cell cycle regulation, apoptosis, and oncogenesis.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 63476-70-0
• MW: 324.38
• Purity: 98.97% (May vary between batches)
• Formula: C₂₂H₁₆N₂O
• SMILES: C(=C1C(=O)C(=CC2=CC(C#N)=CC=C2)CCC1)C3=CC(C#N)=CC=C3
• Target: p53,Histone Acetyltransferase
• Solubility: DMSO:11 mg/mL (33.91 mM)

Bioactivity

• Target IC50:
  p53:0.35 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Benzonitrile, 3,3' [(2 oxo 1,3 cyclohexanediylidene)dimethylidyne]bis, Benzonitrile, 3,3'[(2oxo1,3cyclohexanediylidene)dimethylidyne]bis, p53

Compound Identifiers

PubChem CID

85438922