Bengamide B

SKU: orb1692714

Description

This small molecule is a potent inhibitor of NF-κB activation (IC50 = 85 nM) that blocks IκBα phosphorylation, thereby suppressing pro-inflammatory cytokine production and cancer cell proliferation. It is widely used in research on inflammation, sepsis, and oncology, with applications in both cellular assays and animal models of disease.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 104947-69-5
• MW: 598.81
• Formula: C₃₂H₅₈N₂O₈
• SMILES: CCCCCCCCCCCCCC(=O)O[C@H]1CC[C@H](NC(=O)[C@H](OC)[C@H](O)[C@@H](O)[C@H](O)\C=C\C(C)C)C(=O)N(C)C1
• Target: Others,NF-κB,Interleukin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6444128