Benfotiamine

SKU: orb1225607

Description

Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)protein kinase C (PKC) pathway）of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 22457-89-2
• MW: 466.46
• Purity: >98% (HPLC)
• Formula: C₁₉H₂₃N₄O₆PS
• SMILES: O=C(S/C(CCOP(O)(O)=O)=C(N(CC1=CN=C(C)N=C1N)C=O)/C)C2=CC=CC=C2
• Target: Others
• Solubility: Soluble in DMSO

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Benzoylthiamine monophosphate

Quick Database Links

Gene Symbol

Others