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Belinostat

SKU: orb1225090

Description

Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number414864-00-9
MW318.35
Purity>98% (HPLC)
FormulaC15H14N2O4S
SMILESC1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
TargetHDAC
SolubilityDMSO: 64 mg/mL (201.03 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

PXD101

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Quality Guarantee

Quality Guarantee

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Protocol Information

Available Sizes

Select a size below

5 mg
$ 80.00
10 mg
$ 110.00
25 mg
$ 160.00
50 mg
$ 230.00
100 mg
$ 320.00
200 mg
$ 500.00
500 mg
$ 820.00