Beclobrate

SKU: orb2900828

Description

Beclobrate (Sgd 24774), a Fibric acid derivative, displays remarkable lipid lowering activity in rodents.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 55937-99-0
• MW: 346.85
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₃ClO₃
• SMILES: O=C(OCC)C(OC1=CC=C(C=C1)CC2=CC=C(Cl)C=C2)(C)CC

Bioactivity

• In Vivo:
  On the normal diet rats, Beclobrate lowers total plasma cholesterol by 22-33.4% (10-50 mg/kg); the cholesterol reduction occurred mainly in high density lipoproteins (HDL). In addition, Beclobrate administration dramatically increases the activity of the high-affinity receptors for beta-VLDL in isolated liver membranes.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only