Beclin1-ATG14L interaction inhibitor 1

SKU: orb2277711

Description

COM 19 is a selective small molecule inhibitor that disrupts the Beclin1-ATG14L interaction, specifically blocking VPS34 complex I formation and autophagy initiation while sparing complex II. This tool compound is used in vitro and in vivo to study selective autophagy inhibition in cancer and neurodegenerative disease research.

Research Area

Infectious Disease & Virology; Pharmacology & Drug Discovery; Cell Biology

Images & Validation

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Key Properties

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CAS Number	1243063-73-1
MW	468.53
Formula	C₂₃H₂₄N₄O₅S
SMILES	O=C1N(C2=CC(=CC=C2OC1)S(=O)(=O)NC3=CC=CC(=C3C)C)CC4=NOC(=N4)C5CCC5
Target	Autophagy

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

50824669 ↗

Key Properties

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No computed properties available.

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