Becatecarin

SKU: orb1985052

Description

Becatecarin is a water-soluble rebeccamycin analog that acts as a dual topoisomerase I/II inhibitor by intercalating DNA and stabilizing the topoisomerase-DNA complex, leading to DNA cleavage and apoptosis. Its anticancer and myelosuppressive effects have been studied in vivo, and it is a known substrate of the ABCG2 transporter.

Research Area

Molecular Biology

Key Properties

• CAS Number: 119673-08-4
• MW: 669.56
• Formula: C₃₃H₃₄Cl₂N₄O₇
• SMILES: CCN(CC)CCN1C(=O)c2c(C1=O)c1c3cccc(Cl)c3n([C@@H]3O[C@H](CO)[C@@H](OC)[C@H](O)[C@H]3O)c1c1[nH]c3c(Cl)cccc3c21
• Target: Topoisomerase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

101524