BEBT-908

SKU: orb1307880

Description

BEBT-908 is a potent small molecule inhibitor with dual activity, selectively targeting PI3Kα (IC50 <0.1 μM) and inhibiting HDAC (IC50 0.1-1 μM). This profile supports its investigation in oncology research for studying signaling pathways and epigenetic regulation in both cellular and animal models of cancer.

Research Area

Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 1235449-52-1
• MW: 507.57
• Purity: 99.67% (May vary between batches)
• Formula: C₂₃H₂₅N₉O₃S
• SMILES: CNc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1
• Target: HDAC,PI3K
• Solubility: DMSO:35 mg/mL (68.96 mM)

Bioactivity

• Target IC50:
  HDAC:0.1 μM|PI3Kα:0.1 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BEBT 908, BEBT908, BEBT-908, HDAC, MDK9521, MDK-9521, MDK 9521, Inhibitor, inhibit, PI3K, PI3Ka inhibitor 1, PI3Kalpha inhibitor 1, PI3Kα, PI3Kα inhibitor 1, Phosphoinositide 3-kinase

Compound Identifiers

PubChem CID

59474330