Beauveriolide III

SKU: orb1693925

Description

Beauveriolide III is a fungal cyclodepsipeptide that inhibits cholesterol synthesis (IC50=0.41 µM) and ACAT activity (IC50=5.5 µM), thereby reducing lipid droplet formation. It has demonstrated anti-atherosclerotic effects, significantly decreasing lesion size in Ldlr-/- and ApoE-/- mouse models at doses of 25-50 mg/kg.

Research Area

Neuroscience

Key Properties

• CAS Number: 221111-70-2
• MW: 487.63
• Purity: 99.48% (May vary between batches)
• Formula: C₂₇H₄₁N₃O₅
• SMILES: C([C@@H]1NC(=O)C[C@@]([C@H](CCCC)C)(OC(=O)[C@@]([C@H](CC)C)(NC(=O)[C@H](C)NC1=O)[H])[H])C2=CC=CC=C2
• Target: Beta Amyloid
• Solubility: Methanol:Soluble;DMSO:Soluble

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Beauveriolide III, BeauveriolideIII

Compound Identifiers

PubChem CID

9848317