BE-16627B

SKU: orb1738646

Description

BE-16627B is a selective metalloproteinase inhibitor isolated from Streptomyces sp., effectively suppressing enzymes like stromelysin and 92 kDa gelatinase. It demonstrates dose-dependent inhibition of collagenolysis (IC50 = 25 µM) in synovial cell cultures without cytotoxicity, making it a valuable research tool for studying matrix remodeling in arthritis and cancer models.

Key Properties

• CAS Number: 137530-61-1
• MW: 375.42
• Formula: C₁₆H₂₉N₃O₇
• SMILES: C(C(N[C@H](C(N[C@@H]([C@@H](C)C)C(O)=O)=O)CO)=O)(CC(NO)=O)CC(C)C
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132070