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BDTX-189

SKU: orb1218309

Description

BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.

Images & Validation

Key Properties

CAS Number2414572-47-5
MW561.03
Purity>98% (HPLC)
FormulaC29H29ClN6O4
SMILESC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)OCCN5CCOCC5
TargetBTK
SolubilityDMSO:41.67 mg/mL (74.27 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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BDTX-189 (orb1218309)

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Available Sizes

Select a size below

500 mg
2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 160.00
25 mg
$ 290.00
50 mg
$ 510.00
100 mg
$ 740.00
200 mg
$ 1,040.00