BDE 47

SKU: orb3211573

Description

BDE-47 induces apoptosis in zebrafish embryonic cells by promoting ROS generation, activating the JNK signaling pathway, and targeting mitochondria to suppress oxidative phosphorylation and reduce membrane potential, accompanied by stress-induced activation of the Nrf2 pathway, ultimately leading to embryonic developmental toxicity.

Key Properties

• CAS Number: 5436-43-1
• MW: 485.8
• Purity: 97.65% (May vary between batches)
• Formula: C₁₂H₆Br₄O
• SMILES: BrC1=CC=C(OC2=CC=C(Br)C=C2Br)C(Br)=C1
• Target: OXPHOS,Nrf2,ROS,Apoptosis,JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

OXPHOS,Nrf2,ROS,Apoptosis,JNK