BCRP-IN-2

SKU: orb2814228

Description

BCRP-IN-2 is a UV-activated BCRP inhibitor that stimulates ATP hydrolysis, enhancing mitoxantrone accumulation in resistant H460/MX20 cells. It is a valuable quinazoline-based chemical probe for studying BCRP-mediated multidrug resistance in cancer research, applicable in both in vitro and cellular efflux assays.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2953730-35-1
• MW: 339.35
• Formula: C₁₉H₁₃N₇
• SMILES: [N-]=[N+]=NC1=CC=C(C=C1)NC2=NC(=NC3=CC=CC=C32)C=4C=CN=CC4
• Target: BCRP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361407