BCR-ABL-IN-6

SKU: orb1686593

Description

BCR-ABL-IN-6 (9h) is a potent and selective imatinib-derived Bcr-Abl kinase inhibitor, active against both wild-type (IC50 = 4.6 nM) and the T315I mutant (IC50 = 277 nM). This compound is a valuable research tool for investigating chronic myeloid leukemia (CML) in biochemical and cellular assays.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2499499-26-0
• MW: 505.49
• Formula: C₂₇H₂₂F₃N₅O₂
• SMILES: C(F)(F)(F)C1=C(C=CC(C(NC2=CC(C#CC3=C4C(NN=C4N)=CC=C3)=CC=C2)=O)=C1)N5CCOCC5
• Target: Others,Bcr-Abl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155400340