BCR-ABL-IN-5

SKU: orb1686711

Description

BCR-ABL-IN-5 is a potent inhibitor of both wild-type and T315I mutant Bcr-Abl kinase, with respective IC50 values of 0.014 μM and 0.45 μM. It demonstrates anti-proliferative activity in leukemic cell studies and serves as a valuable research tool for investigating chronic myeloid leukemia (CML) resistance mechanisms in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1795736-60-5
• MW: 494.37
• Formula: C₂₅H₂₁Cl₂N₅O₂
• SMILES: NC=1C2=C(C=CC=C2NN1)C3=CC=C(C(=O)N4CCN(C(=O)C5=C(Cl)C=C(Cl)C=C5)CC4)C=C3
• Target: Bcr-Abl,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122196083