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BCR-ABL-IN-3

SKU: orb1691097

Description

BCR-ABL-IN-3 is a potent, irreversible Bcr-Abl inhibitor with an IC50 of ≤100 nM against the T315I mutant in Ba/F3 cells. It demonstrates significant anti-cancer activity and is a valuable tool for investigating resistance mechanisms in chronic myeloid leukemia research, both in vitro and in vivo.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2240191-12-0
MW466.89
FormulaC20H17ClF2N4O3S
SMILESO[C@@H]1CCN(C1)c1ncc(cc1-c1cnsc1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1
TargetOthers,Bcr-Abl

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

BCR-ABL-IN-3 (orb1691097)

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