BCR-ABL-IN-2

SKU: orb1710299

Description

BCR-ABL-IN-2 is a potent small molecule inhibitor targeting the BCR-ABL1 kinase, with IC50 values of 57 nM for the native protein and 773 nM for the T315I mutant. It serves as a valuable research tool for in vitro studies of chronic myeloid leukemia (CML) and drug resistance mechanisms.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 897369-18-5
• MW: 502.39
• Formula: C₂₄H₂₅Cl₂N₅O₃
• SMILES: N(C(NC1=C(Cl)C(Cl)=CC=C1)=O)C=2N(N=C(C(C)(C)C)C2)C=3C=C4C(=CC3)CN[C@H](C(O)=O)C4
• Target: Others,Bcr-Abl

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11854202