BCL6-IN-3

SKU: orb1710301

Description

BCL6-IN-3 is a potent small molecule inhibitor of BCL6, demonstrating a GI50 of 70 nM in SU-DHL4 lymphoma cells. It modulates processes such as cell differentiation and apoptosis and shows promising antitumor activity in research models, supporting its use in oncology and hematology studies.

Research Area

Cell Biology, Immunology & Inflammation, Molecular Biology

Key Properties

• CAS Number: 2253878-44-1
• MW: 508.99
• Purity: 97.25% (May vary between batches)
• Formula: C₂₄H₃₁ClF₂N₆O₂
• SMILES: C(CC(C)(C)O)N1C=2C(N(C)C1=O)=CC=C(NC3=NC(=NC=C3Cl)N4C[C@H](C)C(F)(F)[C@H](C)C4)C2
• Target: DNA,Bcl-2 Family,Bcl-6
• Solubility: DMSO:180 mg/mL (353.64 mM)

Bioactivity

• Target IC50:
  Proliferation (SU-DHL4 cells):70 nM (GI50)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNA, Bcl-6, BCL6 IN 3, BCL6IN3, BCL-6-IN-3, BCL6-IN-3, SU-DHL4 cells proliferation

Compound Identifiers

PubChem CID

135386938