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Bcl-2/Mcl-1-IN-5

SKU: orb3211496

Description

Bcl-2/Mcl-1-IN-5 (Compound S6) is an inhibitor targeting Bcl-2 and Mcl-1. It facilitates apoptosis by downregulating anti-apoptotic proteins Bcl-2 and Mcl-1, induces mitochondrial membrane depolarization, and activates caspase-dependent apoptotic cascades, as evidenced by Caspase-3 activation and PARP1 cleavage. Additionally, Bcl-2/Mcl-1-IN-5 exhibits anti-hepatocellular carcinoma activity.

Images & Validation

Key Properties

TargetCaspase,Bcl-2 Family,PARP,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information