Bcl-2-IN-21

SKU: orb2663637

Description

Bcl-2-IN-21 (C1) is an iridium(III)-based complex that acts as a Bcl-2 inhibitor, disrupting mitochondrial function to induce apoptosis via Bax upregulation and caspase-3 activation. It demonstrates potent anti-proliferative activity in vitro by suppressing cancer cell colony formation and has shown efficacy in vivo in murine tumor models.

Research Area

Cell Biology

Key Properties

• MW: 980.96
• Formula: C₄₅H₃₃F₆IrN₅P
• Target: Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Bcl-2 Family