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Bcl-2-IN-21

SKU: orb2663637

Description

Bcl-2-IN-21 (C1) is an iridium(III)-based complex that acts as a Bcl-2 inhibitor, disrupting mitochondrial function to induce apoptosis via Bax upregulation and caspase-3 activation. It demonstrates potent anti-proliferative activity in vitro by suppressing cancer cell colony formation and has shown efficacy in vivo in murine tumor models.

Research Area

Cell Biology

Images & Validation

Key Properties

MW980.96
FormulaC45H33F6IrN5P
TargetBcl-2 Family

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Bcl-2-IN-21 (orb2663637)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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