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BChE-IN-49

SKU: orb3210372

Description

BChE-IN-49 is an orally active BChE inhibitor with IC50 values of 0.73 μM for BChE and 6.43 μM for AChE. It reduces AChE levels to inhibit acetylcholine degradation. By inhibiting GSK-3β, BChE-IN-49 robustly activates the Wnt/β-catenin signaling pathway, exhibiting potent anti-Aβ, antioxidant, anti-neuroinflammatory, and anti-apoptotic effects. BChE-IN-49 is applicable in Alzheimer's disease research.

Images & Validation

Key Properties

TargetBeta Amyloid,Interleukin,GSK-3,TNF,Cholinesterase (ChE),Bcl-2 Family,Apoptosis,Wnt/beta-catenin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information