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BC-DXI-495

SKU: orb3218140

Description

BC-DXI-495 is an AIMP2-DX2 inhibitor that promotes Siah1-mediated ubiquitination and degradation of DX2 by interfering with the binding of DX2 to HSP70, thereby inhibiting tumor cell proliferation that depends on DX2. BC-DXI-495 shows in vivo antitumor activity in lung cancer research and can serve as a chemical probe for studying DX2-related mechanisms.

Images & Validation

Key Properties

CAS Number2421117-94-2
MW518.63
Purity99.52% (May vary between batches)
FormulaC28H30N4O4S
SMILESC([C@H](NS(=O)(=O)C1=CC=C(C)C=C1)C(NC2=CC=C(C=C2)N3CCOCC3)=O)C=4C=5C(NC4)=CC=CC5
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

Available Sizes

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1 mg
$ 80.00
5 mg
$ 130.00
10 mg
$ 170.00
25 mg
$ 270.00
50 mg
$ 410.00
100 mg
$ 620.00
DispatchUsually dispatched within 5-10 working days
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