BC 11 hydrobromide

SKU: orb1704663

Description

BC-11 hydrobromide is a selective dual inhibitor of TMPRSS2 and urokinase (uPA). Its mechanism involves reducing mitochondrial function, increasing ROS generation, and inducing apoptosis, making it a useful research tool for studying breast cancer in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 443776-49-6
• MW: 290.97
• Purity: 99.64% (May vary between batches)
• Formula: C₈H₁₂BBrN₂O₂S
• SMILES: Br.N=C(SCC1=CC=C(C=C1)B(O)O)N
• Target: SARS-CoV,ROS,PAI-1,Apoptosis,Serine Protease
• Solubility: H2O:15 mg/mL (51.55 mM);DMSO:100 mg/mL (343.68 mM)

Bioactivity

• Target IC50:
  uPA:8.2 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, BC11 Hydrobromide, BC-11 Hydrobromide, uPA, ROS, SerineProtease, Serine Protease

Compound Identifiers

PubChem CID

78243712