BC 11-38

SKU: orb1306171

Description

BC 11-38 is a potent and selective small molecule inhibitor of phosphodiesterase 11 (PDE11A), exhibiting an IC50 of 0.28 µM. This research compound is a valuable tool for investigating PDE11A's role in cellular signaling, neurobiology, and endocrine function in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 686770-80-9
• MW: 304.43
• Purity: 99.28% (May vary between batches)
• Formula: C₁₅H₁₆N₂OS₂
• SMILES: CCCSc1nc2CCSc2c(=O)n1-c1ccccc1
• Target: PDE
• Solubility: 10% DMSO+90% Corn Oil:2.5 mg/mL (8.21 mM);DMSO:50 mg/mL (164.24 mM)

Bioactivity

• Target IC50:
  PDE10:>100 μM|PDE11:0.28 μM
• In Vitro:
  BC 11-38 ignificantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cortisol, cells, BC11-38, BC 11 38, BC 1138, BC 11-38, cAMP, adrenocortical, Inhibitor, levels, inhibit, PDE11, Phosphodiesterase (PDE), production

Compound Identifiers

PubChem CID

2052828