BBT-176

SKU: orb3209961

Description

BBT-176 is an orally effective EGFR inhibitor. BBT-176 has inhibitory activity against multiple EGFR C797S mutant cell lines. BBT-176 is commonly used in cancer research contexts involving EGFR-mutant signaling pathway models, where BBT-176 is applied to study kinase inhibition profiles, resistance-associated EGFR mutations such as C797S, and downstream proliferative signaling modulation in cell-based experimental systems.

Key Properties

• CAS Number: 2254805-44-0
• MW: 601.16
• Purity: 99.91% (May vary between batches)
• Formula: C₂₈H₃₇ClN₈O₃S
• SMILES: O=S(=O)(NC=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCC(N5CCN(C)CC5)CC4)C
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR