BB-Cl-Yne

SKU: orb3177639

Description

BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-CL-Yne inhibits PAD1-4 with Kinact/KI values of 6,400, 3,600, 10,800, and 4,900 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2219324-71-5
• MW: 483.99
• Formula: C₂₈H₂₆ClN₅O
• SMILES: [C@H](NC(=O)C1=CC=C(C=C1)C2=CC=C(C#C)C=C2)(CCCNC(CCl)=N)C=3NC=4C(N3)=CC=CC4
• Target: Others,PAD

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,PAD