BAZ1A-IN-1

SKU: orb1298027

Description

BAZ1A-IN-1

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 941521-45-5
• MW: 340.36
• Purity: 99.91% (May vary between batches)
• Formula: C₁₆H₁₂N₄O₃S
• SMILES: [O-][N+](=O)c1cccc(NC(=O)Nc2nc(cs2)-c2ccccc2)c1
• Target: Epigenetic Reader Domain
• Solubility: DMSO:80 mg/mL (235.05 mM)

Bioactivity

• Target IC50:
  BAZ1A:0.52 μM(Kd)|BAZ1A:5.08 μM (THP-1), 4.29 μM(ZR-75-30), 10.65 μM(BT474),7.70 μM(H1975 cells)
• In Vitro:
  Administration of BAZ1A-IN-1 (0.015-100 μM; 96 hours) exhibits good anti-viability activity against all the four cancer cell lines that have a high expression level of BAZ1A, with IC50 values of 5.08 μM, 4.29 μM, 10.65 μM, and 7.70 μM for THP-1, ZR-75-30, BT474, and H1975 cells, respectively.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

THP-10, ZR-75–30, inhibit, lung cancer, EpigeneticReaderDomain, Epigenetic Reader Domain, H1975, Inhibitor, leukemia, BAZ1A, BAZ1A IN 1, BAZ1AIN1, BAZ-1A-IN-1, BAZ1A-IN-1, bromodomain-containing, BT474, cancer, breast cancer

Compound Identifiers

PubChem CID

19257149