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BAY885

SKU: orb1218369

Description

BAY885 is a new ERK5 inhibitor.

Images & Validation

Key Properties

CAS Number2307249-33-6
MW515.53
Purity>98% (HPLC)
FormulaC25H28F3N7O2
SMILESCN1CCN(CC1)C2=CC3=C(C(=NC=N3)C4CCN(CC4)C(=O)C5=C(C=C(C=C5)OC(F)(F)F)N)N=C2
TargetERK
SolubilityDMSO:16.67 mg/mL (32.34 mM; Need ultrasonic)

Bioactivity

In Vitro
The ERK5 probe 41 (BAY-885) showed potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and had no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM).

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • BAY885 [orb1309941]

    99.83% (May vary between batches)

    2307249-33-6

    515.53

    C25H28F3N7O2

    1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 1 ml x 10 mM (in DMSO)
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Protocol Information

Available Sizes

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100 mg
200 mg
500 mg
2 mg
$ 400.00
5 mg
$ 590.00
10 mg
$ 870.00
25 mg
$ 1,390.00
50 mg
$ 1,880.00