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Catalog Number | orb1303859 |
---|---|
Category | Small Molecules |
Description | BAY-876 |
CAS Number | 1799753-84-6 |
Purity | 97.37% |
MW | 496.42 |
SMILES | Cc1c(NC(=O)c2cc(nc3cc(F)ccc23)C(N)=O)c(nn1Cc1ccc(cc1)C#N)C(F)(F)F |
Formula | C24H16F4N6O2 |
Biological Activity | BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits > 130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabolism and ovarian cancer growth. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |