BAY-846

SKU: orb1739347

Description

BAY-846 is a potent and selective allosteric MEK inhibitor characterized by favorable pharmacokinetics, including a long half-life and high oral bioavailability with low brain penetration. It demonstrates significant anti-tumor efficacy in preclinical studies, particularly in K-Ras mutant models like the A549 xenograft, supporting its use in oncology research targeting the MAPK pathway.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1836185-18-2
• MW: 596.29
• Formula: C₁₉H₁₃F₄IN₄O₄S
• SMILES: C(N)(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1OC3=CC(NS(N)(=O)=O)=C(F)C=C3
• Target: MEK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

127038617