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BAI1

SKU: orb1221038

Description

BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number335165-68-9
MW467.2
Purity>98% (HPLC)
FormulaC19H21Br2N3O
SMILESOC(CN1CCNCC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc12
TargetBcl-2
SolubilityDMSO: 15 mg/mL (32.1 mM);Water: Insoluble

Bioactivity

In Vitro
Apoptosis Analysis Cell line: Mouse MEF. Concentration: 0.3125 μM, 0.625 μM, 1 μM, 1.25 μM, 1.5 μM, 2.5 μM, 3 μM, 4 μM, 5 4 μM, 10 4 μM Incubation time: 8 hours. Result: Inhibited cell death in BAX-dependent manner.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

BAI1 (orb1221038)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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200 mg
500 mg
2 mg
$ 90.00
5 mg
$ 140.00
10 mg
$ 220.00
25 mg
$ 410.00
50 mg
$ 730.00
100 mg
$ 1,060.00