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BAG3/HSP70-IN-1

SKU: orb2944600

Description

USP1-IN-11 is a selective, reversible, non-competitive USP1 inhibitor that activates the DNA damage response, inducing cell cycle arrest and apoptosis. It synergizes with agents like Olaparib and Andrographolide in vitro and shows dose-dependent antitumor efficacy in MDA-MB-436 xenograft models in vivo.

Research Area

Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

MW537.65
FormulaC28H39N7O4
TargetApoptosis,Caspase,HSP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

BAG3/HSP70-IN-1 (orb2944600)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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