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BACE-1 inhibitor 1

SKU: orb1710335

Description

Compound 8a is a potent small molecule inhibitor of BACE-1, exhibiting an IC50 value of 56 nM. This inhibitor is a valuable research tool for studying Alzheimer's disease pathogenesis and for conducting in vitro enzymatic assays and cellular studies targeting beta-amyloid production.

Research Area

Neuroscience, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number1262858-14-9
MW443.22
FormulaC17H14BrF3N4O2
SMILESC(F)(F)[C@@]1(N=C(N)COC1)C2=CC(NC(=O)C3=CC=C(Br)C=N3)=CC=C2F
TargetOthers,Beta-Secretase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information