Azurin p28 peptide

SKU: orb2276958

Description

The Azurin p28 peptide is a cell-penetrating antitumor agent that stabilizes p53 by inhibiting its proteasomal degradation, leading to cell cycle arrest or apoptosis in p53-positive tumors. It also demonstrates antiangiogenic activity by suppressing VEGFR-2, FAK, and Akt phosphorylation, as shown in both in vitro and in vivo cancer research models.

Research Area

Cell Biology

Key Properties

• Target: MDM-2/p53,Apoptosis
• CAS Number: 897026-25-4
• MW: 2914.18
• Formula: C₁₂₂H₁₉₇N₃₁O₄₇S₂
• SMILES: C([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)CO)=O)[C@@H](C)O)=O)C)=O)C)=O)CC(O)=O)=O)CCSC)=O)CCC(N)=O)=O)=O)[C@@H](C)C)=O)C(C)C)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCSC)=O)C)=O)CO)=O)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)=O)CC(C)C)=O)CCCCN)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)CC(O)=O)=O)CCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

53363312