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Azo-PROTAC-4C-trans

SKU: orb3177212

Description

Azo-PROTAC-4C-trans is a BCR-ABL PROTAC degrader that efficiently targets BCR-ABL fusion proteins and ABL proteins. It exhibits strong, selective antiproliferative activity against K562 cells. The activity of Azo-PROTAC-4C-trans can be precisely and reversibly controlled through UV (for inactivation)/visible light (for activation) irradiation. This compound is applicable for myeloid leukemia research.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

TargetPROTACs,Bcr-Abl

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information