Azlocillin sodium

SKU: orb1225175

Description

Azlocillin is an acylampicillin with a broad spectrum against bacteria.(In Vitro):Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin.(In Vivo):Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae.

Key Properties

• CAS Number: 37091-65-9
• MW: 483.47
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₂N₅NaO₆S
• SMILES: O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3CCNC3=O)=O)C4=CC=CC=C4)=O)N1C2=O)[O-].[Na+]
• Target: Antibacterial
• Solubility: Ethanol: 3 mg/mL (6.19 mM); Water: 97 mg/mL (200.21 mM); DMSO: 97 mg/mL (200.21 mM)

Bioactivity

• In Vivo:
  Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae.
• In Vitro:
  Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Azlocillin sodium salt | Sodium Azlocillin | Securopen | Bay-e 6905 | Azlocillin

Quick Database Links

Gene Symbol

Antibacterial