AZD9977

SKU: orb1298438

Description

AZD9977 is a selective mineralocorticoid receptor modulator developed for research. It has been investigated in preclinical models for cardiorenal diseases, showing differentiated effects on sodium excretion and potassium retention in both in vitro and in vivo studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1850385-64-6
• MW: 399.37
• Purity: 99.92% (May vary between batches)
• Formula: C₂₀H₁₈FN₃O₅
• SMILES: CNC(=O)C[C@H]1COc2cc(F)ccc2N1C(=O)c1ccc2OCC(=O)Nc2c1
• Target: Glucocorticoid Receptor
• Solubility: DMSO:27.5 mg/mL (68.86 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (5.01 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Chronic Kidney Disease, ?type 2 diabetes mellitus, AZD 9977, AZD9977, AZD-9977, Heart Failure, GlucocorticoidReceptor, Glucocorticoid Receptor, mineralocorticoid receptor, Mineralocorticoid Receptor, Inhibitor, inhibit, T2DM

Compound Identifiers

PubChem CID

118599727